Monday, November 28, 2011

US court won't block its Texas redistricting map (AP)

AUSTIN, Texas ? A federal court refused late Friday to block a congressional redistricting map it drew up for Texas, rejecting a request from the state's attorney general just hours after the Republican accused the court of "undermining the democratic process."

Texas Attorney General Greg Abbott had asked the San Antonio-based court to stay the implementation of its interim map, which the court drafted when minority groups challenged the original plan passed by the Republican-dominated state Legislature.

The court-drawn map would ensure minorities made up the majority in three additional Texas congressional districts. If the 2012 elections were held under the court's map, Democrats would have an advantage as they try to win back the U.S. House.

Abbott said he would appeal to the U.S. Supreme Court. The court-ordered map will remain in place until the legal fights are resolved.

The court drew the maps after minority groups filed a lawsuit, claiming a redistricting plan devised by Republican lawmakers didn't reflect growth in the state's Hispanic and black populations.

In a court filing earlier Friday, Abbott accused the court of overstepping its authority.

"A court's job is to apply the law, not to make policy," he wrote. "A federal court lacks constitutional authority to interfere with the expressed will of the state Legislature unless it is compelled to remedy a specific, identifiable violation of law."

Abbott argued that the Legislature's map "incorporate constituents' concerns about communities of interest and proper representation." He said the court's departure from that map "not only undermines the democratic process, it ignores the voice of the citizenry."

Lawmakers redraw boundaries for the state's legislative districts every 10 years to reflect changes in census data. Texas' population boom in the last decade gave it four new U.S. House seats, which will be filled in the 2012 election.

Like other states with a history of racial discrimination, Texas can't implement those new maps or other changes to voting practices without federal approval under the Voting Rights Act. No federal approval, and looming deadlines for county election officials, made it necessary for the court to issue its own plans ? which could be implemented immediately.

Minorities currently are the majority in 10 of Texas' 32 congressional districts. The new court-drawn map would raise that to 13 out of 36 districts.

Republican lawmakers insist the maps drawn by the Legislature merely reflect the Republican majority in Texas. Experts say that under the legislatively approved map, three of the new seats would likely be won by Republicans.

When drawing the interim map, the court gave priority to ensuring minority voting strength was protected in the 2012 election.

In its own filing Friday, the NAACP cheered the court-drawn interim map as a "step forward for Texas." The group said it, "recognizes the growth of the minority population and takes significant steps toward remedying some of the startling lack of proportionality in the prior plans."

Source: http://us.rd.yahoo.com/dailynews/rss/politics/*http%3A//news.yahoo.com/s/ap/20111126/ap_on_re_us/us_texas_redistricting

weather miami ohio state angus t. jones belgian malinois honey badger girl fight jacoby brissett

Wednesday, November 23, 2011

Web of Lies and Secrets Role-Players Needed!

Hello, I'm looking for three role-players for my RP 'Web of Lies and Secrets' Link: roleplay/web-of-lies-and-secrets/

You have known each other since kindergarten, telling each other everything. You have no secrets from each other, or so you think.

When you begin to get letters with no stamp or return address to your house, each containing things that could potentially ruin your friendship and your life, you know that its bad. But when the letters became a stranger following you, overhearing worrying comments that immediately make you think of the things you did...it became too much.

Yet, it was only when you wake up in a room full of sharp objects, tied to a chair and blindfolded that you realise just how dangerous your life has become just because of one mistake of the past...Because the only way to get out of the room alive and moderately unharmed is to spill your secrets...and ruin your life forever.

Who will break first?

Please comment on this thread or PM me if you would like to join, I would appreciate it :)

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/x5nWVsiuGfo/viewtopic.php

rachel uchitel amerigo vespucci julio jones elizabeth warren coptic church steve bartman columbus day

Tuesday, November 22, 2011

No charges recommended for Stevens prosecutors (AP)

WASHINGTON ? The special prosecutor who investigated the botched case against late Alaska Sen. Ted Stevens is not recommending criminal charges against any of the Justice Department attorneys who tried him despite finding widespread misconduct beyond what has yet been publicly revealed.

The findings in a two-and-a-half-year investigation by Washington lawyer Henry F. Schuelke III were revealed Monday in an order from U.S. District Judge Emmet Sullivan. Sullivan wrote the investigation found the Stevens prosecution was "permeated" by the prosecutors' concealment of evidence they collected that could have helped the senator's defense.

The full 500-page report remains under seal until the Justice Department has a chance to respond, but Sullivan says he will release it publicly.

A jury convicted Stevens of seven felony counts of lying on Senate financial disclosure documents to hide hundreds of thousands of dollars in home renovations and gifts from wealthy friends, including a massage chair, a stained-glass window and an expensive sculpture. A few days later, Stevens lost re-election to the seat he'd held for 40 years, making him the longest-serving Republican in the Senate at the time.

Sullivan dismissed the conviction after the Justice Department admitted misconduct in the case, including withholding of notes from an interview with the government's star witness. The witness was Bill Allen, the millionaire founder of a major Alaska company that supported oil producers called VECO Corp., who testified that he oversaw extensive renovations at Stevens' home and sent his employees to work on it.

Sullivan ordered the criminal investigation, saying at the time that he'd never seen such misconduct in 25 years on the bench. He appointed Schuelke, a former prosecutor and veteran white collar defense attorney who oversaw a Senate Ethics Committee investigation into influence-peddling allegations against former New York Sen. Alfonse D'Amato in 1989 and an internal investigation for Jack Abramoff's lobbying firm after his misconduct came to light.

Stevens died in a plane crash last year while the investigation continued.

Sullivan wrote that Schuelke's team uncovered even further evidence of concealment and serious prosecutorial misconduct that almost certainly would never have been revealed publicly or to him without the exhaustive investigation that reviewed more than 150,000 pages of documents, interviewed numerous witnesses, and conducted twelve depositions. The investigators also found at least some of the concealment was intentional.

But Schuelke did not recommend criminal contempt charges because the judge never issued a direct order spelling out the rules of evidence.

"Because the court accepted the prosecutors' repeated assertions that they were complying with their obligations and proceeding in good faith, the court did not issue a clear and unequivocal order directing the attorneys to follow the law," Sullivan wrote.

Subjects of the criminal investigation were prosecutors Brenda Morris, Edward Sullivan, Joseph Bottini, James Goeke and William Welch, who did not participate in the trial but at the time supervised the Justice Department's Public Integrity section and had overseen every major public corruption case in recent years.

Another attorney who was targeted in the investigation, Nicholas Marsh, committed suicide last year.

The Justice Department also conducted a separate, internal investigation and found in a draft report that Alaska-based prosecutors Bottini and Goeke and FBI agent Mary Beth Kepner engaged in misconduct in the trial, according to a lawyer familiar with the investigation. Lawyers familiar with that investigation by the department's Office of Professional Responsibility told The Associated Press that it remains open.

Kepner came under scrutiny after an FBI whistle-blower said Kepner had an inappropriate relationship with the star witness in the case. Beth Kepner's lawyer, Michael Schwartz, said last month his client has cooperated with the OPR investigation, continues to do so and remains an agent of the FBI assigned to the Alaska division.

Last month, Chuck Rosenberg, a lawyer for Morris, said that OPR found no misconduct by his client.

___

Associated Press writer Pete Yost contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/uscongress/*http%3A//news.yahoo.com/s/ap/20111121/ap_on_go_co/us_stevens_investigation

courtney stodden drake take care herman cain accuser herman cain accuser election day kawasaki disease joe frazier

Monday, November 21, 2011

Patti Stanger's Advice For Demi Moore: 'Hang In There!' (omg!)

Patti Stanger, Demi Moore -- Access Hollywood / Getty Images

As the star of Bravo's "The Millionaire Matchmaker," Patti Stanger is in the business of finding people who fit romantically, and on Friday, the relationship guru weighed in on why she thinks Demi Moore and Ashton Kutcher split.

"What it is, is that there's a 16-year age difference in the older female and younger male," Patti told Access Hollywood . "I don't think it can work."

PLAY IT NOW: Demi Moore & Ashton Kutcher: It's Over!

Patti, who continues her own search for love in this Tuesday's season finale of "The Millionaire Matchmaker," thinks the opposite equation - an older man with a younger woman, is a good fit.

"In my opinion, I think the other way can [work]," she said. "In this case, Ashton's young, with money. He doesn't need her money; he's very successful; he owns half of Silicon Valley; he's invested in every major Internet company out there. The second thing is, he's looking good, he's back on TV, he's got pep in his step and he's hitting the blondes. What's up with that?"

VIEW THE PHOTOS: Celebs Who Moved To Splitsville In 2011

Patti, who has also had her personal relationship ups and downs, said she could relate to Demi.

"She's getting to a different level in her life," the Bravo star said. "It's almost like her window's closing and his is opening. And it's sad, because I'm her age, I know exactly what it feels like to feel like, you know, 'Is my tour of duty over?' And I say to Demi, 'Hang in there! But you need to date older - in your own age group.'"

While it's unlikely Demi will be spotted dating any time soon, Patti said when the time is right, Demi should look for someone with similar values.

VIEW THE PHOTOS: They Dated? Surprising Former Couples!

"I think she needs to find someone spiritual. She's very involved in the Kabbalah Center. I don't get the sense that Ashton is really in it for himself as far as Kabbalah is goes, to heighten himself. I think he did it for Demi," Patti said. "I think she needs to find someone in her own age group who's probably outside of Hollywood who's a business owner."

"The Millionaire Matchmaker" season finale airs Tuesday on Bravo. The reunion shows, hosted by Andy Cohen, air on Bravo on November 29 and December 6 at 9 PM ET/PT.

VIEW THE PHOTOS: Keepin? It Real With TV?s Hottest Reality Stars!

Copyright 2011 by NBC Universal, Inc. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://us.rd.yahoo.com/dailynews/rss/entertainment/*http%3A//us.rd.yahoo.com/dailynews/external/omg_rss/rss_omg_en/news_patti_stangers_advice_demi_moore_hang200819239/43648555/*http%3A//omg.yahoo.com/news/patti-stangers-advice-demi-moore-hang-200819239.html

la auto show pumpkin cheesecake oregon usc powerball winning numbers powerball winning numbers black friday 2011 deals uc davis pepper spray

Wednesday, November 16, 2011

Gearing Up For Asia Expansion, Bubble Motion Makes A Number of Executive Hires

bubbleBubble Motion, which offers a popular a Twitter-like voice blogging service in India, Japan, and Indonesia, is announcing a number of high-profile executive hires to support its future growth in Asia. Bubble Motion?s Bubbly platform is a voice-blogging phone service that allows people to share status updates in their own voice with fans and followers. It essentially takes Twitter's model and applies this to voice blogging and mobile phones. These ?bubblers? record their voice update into their phone, and their followers everywhere are notified by SMS and prompted to click and listen.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/rX5TBzmBoqQ/

chanukah 11 11 11 meaning miracle berry billy crystal veterans day thank you veterans day thank you nigel tufnel day

Tuesday, November 15, 2011

Today's Lifehacker Workout: We're in the Home Stretch! [Video]

Today's Lifehacker Workout: We're in the Home Stretch! This is the beginning of the fourth week of our group exercise plan, The Lifehacker Workout. Congrats to everyone who's stuck with the workouts so far, and welcome anyone who's jumping in now.

The video above shows you how to do today's workout: 20 minutes of walking or jogging plus 10 minutes of strength exercises (5 push ups, 10 crunches, 15 squats; repeat). There are video instructions in the playlist above, but you can skip through those 3 to fast forward to the 10-minute looped video showing the core exercise reps. (Following along with that video by Martin Reid of Personal Victory really helps me keep going).

You can also see the challenge and workouts on Fleetly. Let us know how the workouts are going fo you and keep up the good work!

P.S. Here's some extra motivation for you: working out now might make you feel a little less guilty when you have to indulge on Thanksgiving Day.


You can follow or contact Melanie Pinola, the author of this post, on Twitter or Google+.

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/LZ6zz89yjjU/todays-lifehacker-workout-were-in-the-home-stretch

starship troopers starship troopers the skin i live in charlie daniels band

Sunday, November 13, 2011

Cars torched in Jewish neighborhood

Authorities say vandals torched three cars and scrawled Nazi swastikas and other hate messages on benches in a Jewish neighborhood in New York City, infuriating residents and causing thousands of dollars in damage.

The attack happened early Saturday in Brooklyn's Midwood section. Residents woke up at 5:30 a.m. to find the cars engulfed in flames. Someone spray painted the letters "KKK" on a van, and other messages targeting Jews were on the sidewalk.

The act has brought swift condemnation from city officials. Mayor Michael Bloomberg says there's no place for hate in "the freest city in the freest country in the world."

Residents of the neighborhood tell local newspapers that they were outraged. One witness says she saw a group of laughing kids fleeing the scene.

Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.msnbc.msn.com/id/45269342/ns/us_news-crime_and_courts/

tuscaloosa earthquake california earthquake california crimson tide crimson tide wake forest wake forest

Saturday, November 12, 2011

Mid-ocean creatures control light to avoid becoming snacks

Thursday, November 10, 2011

If you're a snack-sized squid or octopus living in the ocean zone where the last bit of daylight gives way, having some control over your reflection could be a matter of life and death.

Most predators cruising 600 to 1,000 meters below the surface spot the silhouette of their prey against the light background above them. But others use searchlights mounted on their heads.

Being transparent and a little bit reflective is a good defense against the silhouette-spotters, but it would be deadly against the "headlight fish," says Duke postdoctoral researcher Sarah Zylinski.

Transparency is the default state of both Japetella heathi, a bulbous, short-armed, 3-inch octopus, and Onychoteuthis banksii, a 5-inch squid found at these depths. Viewed from below against the light background, these animals are as invisible as they can be. Their eyes and guts, which are impossible to make clear, are instead reflective. But when hit with a flash of bluish light like that produced by headlight fish, they turn on skin pigments, called chromatophores, to become red in the blink of an eye.

During ship-board experiments over the Peru-Chile trench in 2010, Zylinski shined blue-filtered LED light on specimens of both creatures to watch them rapidly go from clear to opaque. When the light was removed, they immediately reverted to transparent. On a second research cruise in 2011 in the Sea of Cortez, Zylinski measured the reflectivity of the octopuses and found they reflected twice as much light in their transparent state as in the opaque state.

Zylinski experimented with 15 to 20 different species of cephalopod pulled up from the deep by the research ships, but only these two responded to the blue light. "I went through several things I thought would stimulate behaviors," she says. Shallow-water cephalopods (squid, ocotopi and cuttlefish) will change their body patterns for a shadow or shape passing overhead, but these deeper water animals don't, Zylinski says. The animals could be seen tracking the movements of probes around them, but it was only the light that made them switch on the their pigments.

Zylinski next would like to investigate the link between transparency and habitat depth for the Japetella octopus. "Smaller young animals are found higher in the water column and have fewer chromatophores, so they are more reliant on transparency, which makes sense because there won't be predators using searchlights there," Zylinski says. But the mature adults have a higher density of chromatophores making them potentially more opaque and they can be found in deeper waters (below 800 meters) where bioluminescence becomes the dominant light source.

###

Duke University: http://www.duke.edu

Thanks to Duke University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 98 time(s).

Source: http://www.labspaces.net/115103/Mid_ocean_creatures_control_light_to_avoid_becoming_snacks

oxford comma elisabetta canalis cedric benson lord howe island lord howe island conficker conficker

Friday, November 11, 2011

Satarii Star movement-tracking camera dock finalized as Swivl, now available for reserve (update: video)

If you'll recall, back in January we took notice of an interesting gizmo dubbed Satarii Star -- a movement-tracking dock concept that was seeking funding on IndieGoGo. Well, the unit has since been funded and today the company is re-introducing it as the Swivl. Aside from the updated moniker, it's also sporting an updated feature set and a revamped look. The unit can still house gadgets from iPhones and Androids to pocket camcorders, but improves on the Satarii by adding vertical tilt functionality on top of its 180 degrees of horizontal movement. (Update: We're told that the Swivl can also rotate a full 360 degrees.) Notably, it's stated as being able to "move faster than you can" -- if you're worried about staying in the shot, that is. As it currently stands, we're only seeing renders of this little guy, but the company expects to have fully functional units at CES this January, with units shipping to North America in "early 2012" for about $160. Hopefully we'll get to see the Swivl do its thing on the show floor, but for now, interested parties can reserve their very own at the source link below. You'll find the full press release just past the break.

Update: You'll find a video of a pre-production Swivl in action after the break as well.

Continue reading Satarii Star movement-tracking camera dock finalized as Swivl, now available for reserve (update: video)

Satarii Star movement-tracking camera dock finalized as Swivl, now available for reserve (update: video) originally appeared on Engadget on Wed, 09 Nov 2011 12:00:00 EDT. Please see our terms for use of feeds.

Permalink   |  sourceSwivl  | Email this | Comments


Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/UQFWHDvXUIw/

bet hip hop awards 2011 kraken kraken calvin johnson calvin johnson kenyon martin kenyon martin

Thursday, November 10, 2011

AP Exclusive: Contents of MJ's final home for sale

A photo made Monday, Nov. 7, 2011 shows the bedroom at the Carolwood Drive home where singer Michael Jackson passed away in 2009, in Beverly Hills, Calif. Julien's Auctions will sell various antique furnishings and paintings that surrounded the King of Pop at the home he rented as he prepared for a series of comeback concerts. The auction is set for Dec. 17. (AP Photo/Dan Steinberg)

A photo made Monday, Nov. 7, 2011 shows the bedroom at the Carolwood Drive home where singer Michael Jackson passed away in 2009, in Beverly Hills, Calif. Julien's Auctions will sell various antique furnishings and paintings that surrounded the King of Pop at the home he rented as he prepared for a series of comeback concerts. The auction is set for Dec. 17. (AP Photo/Dan Steinberg)

An image released by Julien's Auctions, shows the cover of the catalog for the Michael Jackson auction. Julien's Auctions will sell various antique furnishings and paintings that surrounded the King of Pop at the Beverly Hills, Calif., home he rented as he prepared for a series of comeback concerts. The auction is set for Dec. 17. (AP Photo/Julien's Auctions)

(AP) ? The bed where Michael Jackson took his last breath is up for sale.

The queen-size piece is among hundreds of items from the Holmby Hills mansion where Jackson spent his final days that are set to hit the auction block next month.

"We want to preserve the history of these items," said celebrity auctioneer Darren Julien, president of Julien's Auctions, which will sell the various antique furnishings, paintings and sculptures that surrounded the King of Pop as he prepared for a series of comeback concerts.

The North Carolwood Drive home where Jackson lived with his three children from December 2008 until his death on June 25, 2009, is separately up for sale. The house and its furnishings were leased to Jackson while he and his family lived there.

A note from one of the children remains on a chalkboard inside the home's sprawling kitchen, where three barstools were lined up against the center island ? a perfect breakfast spot for the kids. "I (heart) Daddy. SMILE, it's for free," the chalk note reads in childlike scrawl. The chalkboard will be sold as-is, and is expected to fetch more than $400.

At the very moment on Monday that Dr. Conrad Murray was convicted of involuntary manslaughter in Jackson's death, reporters were eerily taking a private preview tour of the three-story home where the pop star lived and died.

The bedroom shown in evidence photos at Murray's criminal trial was actually considered a "medication room" by the Jackson team. Murray was found guilty of supplying an insomnia-plagued Jackson with the powerful operating-room anesthetic propofol to help him sleep as he rehearsed for his comeback.

Jackson maintained an adjacent bedroom that he regarded as his inner sanctum ? a private place only for him.

It is in this second bedroom that the pop star wrote a message to himself on the mirror of an antique armoire. "TRAIN, perfection, March April. FULL OUT May," it reads. Jackson was to begin his London concert run in July.

His private bedroom included a bathroom larger than most living rooms and two massive walk-in closets.

Among the items for sale in the medication room, where evidence was collected for Murray's trial, are upholstered chairs smudged with Jackson's makeup and Jackson's death bed, which looks out to an expansive backyard surrounded by tall trees. The yard is anchored by a large swimming pool and a pool house, where the singer's son Prince carved his name on a beeswax candle.

The medication room, on the top floor, leads to another walk-in closet and bathroom, where Jackson's makeup still remains on a small silk-covered stool beneath the vanity.

Curving staircases on each side of the mansion's most famous room lead down to the kitchen and the elegant foyer, where a grand piano sits topped with crystal candlesticks.

The home and its d?cor are reminiscent of Neverland Ranch, Jackson's famous estate near Santa Barbara, said Martin J. Nolan, executive director of Julien's Auctions.

"He loved it because it was like Neverland," Nolan said. "It was a very happy place where he spent his final days."

Julien's Auctions sold collectibles from the Neverland Ranch in April of 2009.

Like Neverland, the Carolwood house features its own movie theater ? this one outfitted entirely in burgundy velvet with loveseat-style sofas and a fresco of a cloud-dotted sky on the ceiling.

Katherine Jackson's attorney, Perry Sanders Jr., said he is aware of the Carolwood auction and has "done everything we can to ascertain that items from this address are not being auctioned using Michael's name and likeness to enhance the items' value."

Built in 2000 and designed by architect Richard Landry, the house at 100 North Carolwood Drive looks like a French chateau and is dominated by 18th and 19th century French d?cor. The walls are lined with various watercolor and acrylic paintings and sculptures fill nooks in the den and family rooms.

The 54,885-square-foot home is for sale, but not up for auction. The price was not disclosed but similar homes in the area are listed at $18 million and up.

The house has six bedrooms and 10 fireplaces. It also has a wine cellar, fitness center and formal dining and sitting rooms.

Photos of the house and the items available for sale are featured in a limited-edition auction catalog, which is being sold for $100. The catalog and auction are carefully titled "100 North Carolwood Drive" and the words "Michael Jackson" are not mentioned in promotional materials.

Highlights from the sale will be on view at a free exhibition at Julien's Auctions in Beverly Hills, Calif., beginning Dec. 12. The auction is set for Dec. 17.

Celebrity home tours still regularly pass by the property. On the day of Murray's conviction, a tour guide could be heard telling passengers, "This is the home of Michael Jackson, where he passed away."

___

AP Entertainment Writer Anthony McCartney contributed to this report.

___

Online:

www.juliensauctions.com

___

AP Entertainment Writer Sandy Cohen is on Twitter. Follow her at www.twitter.com/APSandy.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2011-11-09-Jackson%20House%20Auction/id-8fcc0c7d413e4d4191c1db030a90e0cf

publishers clearing house scare tactics stacy keibler stacy keibler dancing with the stars season 13 cast tay sachs tay sachs

Tuesday, November 8, 2011

HIV study identifies key cellular defence mechanism

ScienceDaily (Nov. 7, 2011) ? Scientists have moved a step closer to understanding how one of our body's own proteins helps stop the human immunodeficiency virus (HIV-1) in its tracks.

The study, carried out by researchers at The University of Manchester and the Medical Research Council's National Institute for Medical Research and published in Nature, provides a blueprint for the design of new drugs to treat HIV infection, say the researchers.

Scientists in the United States and France recently discovered that a protein named SAMHD1 was able to prevent HIV replicating in a group of white blood cells called myeloid cells.

Now, crucially, the teams from Manchester and the MRC have shown how SAMHD1 prevents the virus from replicating itself within these cells, opening up the possibility of creating drugs that imitate this biological process to prevent HIV replicating in the sentinel cells of the immune system.

"HIV is one of the most common chronic infectious diseases on the planet, so understanding its biology is critical to the development of novel antiviral compounds," said Dr Michelle Webb, who led the study in Manchester's School of Biomedicine.

"SAMHD1 has been shown to prevent the HIV virus replicating in certain cells but precisely how it does this wasn't known. Our research has found that SAMHD1 is able to degrade deoxynucleotides, which are the building blocks required for replication of the virus.

"If we can stop the virus from replicating within these cells we can prevent it from spreading to other cells and halt the progress of the infection."

Co-author Dr Ian Taylor, from the MRC's National Institute for Medical Research, added: "We now wish to define more precisely, at a molecular level, how SAMHD1 functions. This will pave the way for new therapeutic approaches to HIV-1 and even vaccine development."

The study was funded by the Medical Research Council, the European Union Seventh Framework Programme and the European Leukodystrophy Association.

Recommend this story on Facebook, Twitter,
and Google +1:

Other bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Manchester University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. David C. Goldstone, Valerie Ennis-Adeniran, Joseph J. Hedden, Harriet C. T. Groom, Gillian I. Rice, Evangelos Christodoulou, Philip A. Walker, Geoff Kelly, Lesley F. Haire, Melvyn W. Yap, Luiz Pedro S. de Carvalho, Jonathan P. Stoye, Yanick J. Crow, Ian A. Taylor, Michelle Webb. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. Nature, 2011; DOI: 10.1038/nature10623

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/KlrgRbRzcLI/111107033929.htm

denarius moore alley boy alley boy wanda sykes napoleon dynamite bristol palin bethenny frankel

Monday, November 7, 2011

From Nebraska Lab To McDonald's Tray: The McRib's Strange Journey

Fast food giant McDonald's has brought back the McRib until Nov. 14. The sandwich has gained cult acclaim over the past three decades because of its limited availability. Enlarge Paul J. Richards/AFP/Getty Images

Fast food giant McDonald's has brought back the McRib until Nov. 14. The sandwich has gained cult acclaim over the past three decades because of its limited availability.

Paul J. Richards/AFP/Getty Images

Fast food giant McDonald's has brought back the McRib until Nov. 14. The sandwich has gained cult acclaim over the past three decades because of its limited availability.

Since McDonald's announced the seasonal revival of its popular McRib sandwich last month, there's been a round of reports about what's in the sandwich that have ranged from glib (on its 70 ingredients) to McFib (on the alleged inhumane treatment of the pigs that go into it).

But even though there's not a rib to be found inside the sandwich, that pork patty drenched in barbecue sauce actually represents one of the greater innovations in meat science of the last century.

Roger Mandigo is an emeritus University of Nebraska animal science professor credited with the technology that made the McRib possible. And here's its story, straight from the meat scientist's mouth.

? Roger Mandigo earned induction into the Meat Industry Hall of Fame for his invention of "restructured meats." Courtesy of University of Nebraska Institute of Agriculture and Natural Resources

Roger Mandigo earned induction into the Meat Industry Hall of Fame for his invention of "restructured meats."

Back in the 1970s, Mandigo tells The Salt, he was approached by the National Pork Producers Council (the folks who later brought you "the other white meat") to create a product with pork trimmings that could be sold to the fast food giant.

"The pork producers wanted to see more pork on the menu, and they were targeting McDonald's," Mandigo said.

Mandigo went to work in the lab and came up with a new take on an old-fashioned technology: sausage-making. Instead of just stuffing pork meat inside a casing, Mandigo used salt to extract proteins from the muscle. Those proteins become an emulsifier "to hold all the little pieces of meat together," he says.

"All we did was reuse the technology that had been around for hundreds of years and emphasize that we could shape products to shapes people wanted," he says.

And here is where our story takes an interesting twist: Seems the McRib was not born in the shape of its current pork patty. The original concoction Mandigo made was formed as a faux pork chop.

McChop? Maybe not.

"[McDonald's] chose the shape," Mandigo said. "They wanted it to look like the boneless part of a backrib."

That's why Mandigo is adamant that he was not the father of the McRib, despite getting the credit for it all these years.

"We developed the concepts and technology to make the process work," he said. "They developed the sandwich and the form that it's in. That gets a little touchy and sensitive to people, as you might guess."

Despite his modesty, Mandigo's invention of what's called "restructured meats" was important enough to earn him induction into the Meat Industry Hall of Fame, among big names like Colonel Sanders and Wendy's Dave Thomas in the 2010 class.

The restructured meat technology has since been used to make, among other things, chicken nuggets and many other products you see in the grocery store. The largest buyer of restructured meat is the U.S. military, Mandigo said, as the beef, chicken and pork products are convenient for feeding large numbers of people every day.

Now 30 years after his invention in a Nebraska lab, Mandigo is retired. He's good-natured about all the attention he gets every time the McRib comes back on the McDonald's menu ? which this year includes a rogue Twitter account @McRibSandwich.

"It's true. I have 70 ingredients," reads a tweet from Oct. 28. "Ingredient #47 Loch Ness Monster flipper."

Peggy Lowe is a reporter for Harvest Public Media.

Source: http://www.npr.org/blogs/thesalt/2011/11/04/142018151/from-nebraska-lab-to-mcdonalds-tray-the-mcribs-strange-journey?ft=1&f=1007

braves braves harrys law orioles atlanta braves national coffee day national coffee day

Friday, November 4, 2011

New medication effectively treats underlying cause of cystic fibrosis in some patients, study shows

ScienceDaily (Nov. 2, 2011) ? A new study has confirmed that the drug, ivacaftor (VX-770), significantly improves lung function in some people with cystic fibrosis (CF). The results of the phase III clinical trial study, led by Bonnie W. Ramsey, MD of Seattle Children's Research Institute and the University of Washington, were published in the New England Journal of Medicine.

Ivacaftor, also known as VX-770, was developed by Vertex Pharmaceuticals with financial support from the Cystic Fibrosis Foundation. The oral medicine targets the defective protein produced by the gene mutation called G551D that causes CF. Researchers found that patients carrying G551D -- approximately four per cent of all CF patients -- who were treated with VX-770 showed a 17 per cent relative improvement in lung function that was sustained over the course of 48 weeks.

Additionally, patients with G551D treated with VX-770 showed improvements in other areas critically important to the health of people with CF. Study participants experienced significant reductions in sweat chloride levels indicating an improvement in the body's ability to carry salt in and out of cells -- a process which when defective leads to CF. They also experienced decreased respiratory distress symptoms and improved weight gain. Those who received VX-770 gained on average seven pounds compared to those in the placebo group who gained approximately one pound. This is significant because many people with CF have difficulty gaining and maintaining weight due to reduced lung function and chronic infection.

"Our study shows that we are now able to improve the quality of life for cystic fibrosis patients with the G551D mutation with the administration of VX-770," said Dr. Ramsey, director of the Center for Clinical and Translational Research at Seattle Children's Research Institute and endowed chair in Cystic Fibrosis (CF) in the Department of Pediatrics at the University of Washington School of Medicine.

Dr. Ramsey and co-investigators evaluated lung function in patients 12 years or older who carry at least one copy of the G551D mutation. The study included 161 patients at multiple healthcare centers who received at least one dose of VX-770 or placebo. The study is the third and final in a series designed to assess VX-770's effectiveness and safety before it is approved for public use.

Approximately 30,000 children and adults in the United States and 70,000 people worldwide have CF. The disease is caused by a defective gene that affects many parts of the body, but is especially harmful to the lungs and pancreas. The gene mutation causes very thick, sticky mucus to clog the lungs and often cause life-threatening infections. In the 1950s, few children with CF lived beyond age five. Today, advances in research and medical treatments have made it possible for people with CF to live well into their 30s, 40s and beyond.

Co-investigators of this study in the Washington region are: Moira Aitken, MD, professor of medicine in the Division of Pulmonary and Critical Care Medicine at the University of Washington Medical Center and Ronald Gibson, MD, PhD, director of the Cystic Fibrosis Clinical Center at Seattle Children's Hospital and professor of pediatrics at the University of Washington School of Medicine.

Other co-investigators of the study include: Jane Davies, MD, MB, ChB from the Respiratory Biomedical Research Unit, Royal Brompton and Harefield National Health Service Foundation Trust, London; N. Gerard McElvaney, MD from the Royal College of Surgeons and Beaumont Hospital, both in Dublin; Elizabeth Tullis, MD from St. Michael's Hospital, University of Toronto; Scott C. Bell, MB, BS, MD from the Department of Thoracic Medicine, Prince Charles Hospital and Queensland Children's Medical Research Institute, University of Queensland in Brisbane, Australia; Pavel D?ev?nek, MD from the Department of Pediatrics, 2nd Medical School, Charles University, Prague, Czech Republic; Matthias Griese, MD from Dr von Haunersches Kinderspital, University of Munich, Munich, Germany; Edward F. McKone, MD, from St. Vincent's University Hospital in Dublin; Claire E. Wainwright, MD, MB, BS from St. Vincent's University Hospital in Dublin and the Queensland Children's Medical Research Institute, University of Queensland in Brisbane, Australia; Michael W. Konstan, MD from Case Western Reserve University School of Medicine, Rainbow Babies and Children's Hospital, Cleveland; Richard Moss, MD from Stanford University School of Medicine, Stanford, CA; Felix Ratjen, MD, PhD from the University of Toronto Department of Pediatrics and Hospital for Sick Children in Toronto; Isabelle Sermet-Gaudelus, MD, PhD from the Centre d'Investigation Clinique-H?pital Necker, Paris; Steven M. Rowe, MD, MSPH from the University of Alabama at Birmingham, Birmingham; Qunming Dong, PhD, Sally Rodriguez, PhD, Karl Yen, MD and Claudia Ordo?ez, MD from Vertex Pharmaceuticals, Cambridge, MA; and J. Stuart Elborn, MD from the Centre for Infection and Immunity, Queens University Belfast, Belfast, United Kingdom.

Recommend this story on Facebook, Twitter,
and Google +1:

Other bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Seattle Children's.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal References:

  1. Bonnie W. Ramsey, Jane Davies, N. Gerard McElvaney, Elizabeth Tullis, Scott C. Bell, Pavel D?ev?nek, Matthias Griese, Edward F. McKone, Claire E. Wainwright, Michael W. Konstan, Richard Moss, Felix Ratjen, Isabelle Sermet-Gaudelus, Steven M. Rowe, Qunming Dong, Sally Rodriguez, Karl Yen, Claudia Ordo?ez, J. Stuart Elborn. A CFTR Potentiator in Patients with Cystic Fibrosis and theG551DMutation. New England Journal of Medicine, 2011; 365 (18): 1663 DOI: 10.1056/NEJMoa1105185
  2. Pamela B. Davis. Therapy for Cystic Fibrosis ? The End of the Beginning? New England Journal of Medicine, 2011; 365 (18): 1734 DOI: 10.1056/NEJMe1110323

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2011/11/111102190402.htm

americas got talent winner americas got talent winner guinness book of world records gears of war 3 release date up all night dr. oz lingual braces

Thursday, November 3, 2011

Research team unravels tomato pathogen's tricks of the trade

Thursday, November 3, 2011

For decades, scientists and farmers have attempted to understand how a bacterial pathogen continues to damage tomatoes despite numerous agricultural attempts to control its spread.

Pseudomonas syringae pv. tomato is the causative agent of bacterial speck disease of tomato (Solanum lycopersicum), a disease that occurs worldwide and causes severe reduction in fruit yield and quality, particularly during cold and wet springs.

In the spring of 2010, for example, an outbreak in Florida and California devastated the harvest in those areas.

"There is not much that can be done from a farming standpoint," said Boris Vinatzer, associate professor of plant pathology, physiology and weed science, and an affiliated faculty member with the Fralin Life Science Institute at Virginia Tech. "First, farmers try to use seed that is free of the pathogen to prevent disease outbreaks. Then, there are some disease-resistant tomato cultivars, but the pathogen has overcome this resistance by losing the gene that allowed these resistant plants to recognize it and defend themselves. For the rest, there are pesticides but the pathogen has become resistant against them."

So how exactly has the pathogen evolved to consistently evade eradication efforts? This is where science steps in, and a copy of the bacterial pathogen's game plan is crucial.

Thanks to the collaborative work of Vinatzer, Virginia Bioinformatics Institute computer scientist Joao Setubal, assistant professor of statistics Scotland Leman, and their students, the genome of several Pseudomonas syrinage pv. tomato isolates have been sequenced in order to track the bacterial pathogen's ability to overcome plant defenses and to develop methods to prevent further spread.

Their findings were recently published in the Aug. 25 issue of PLoS Pathogens, a peer reviewed open-access journal published by the Public Library of Science.

The research team has studied the pathogen for nearly five years. In 2007, with resources from the Virginia Bioinformatics Institute and the Fralin Life Science Institute, Vinatzer sequenced the genome of Pseudomonas syringae pv. tomato using a Roche GS-FLX ? sequencer at the Virginia Bioinformatics Institute.

In 2008, Vinatzer received a $1 million, five-year Faculty Early Career Development (CAREER) Award from the National Science Foundation to continue investigation of the pathogen. Shortly thereafter, he brought Setubal, a former Virginia Tech faculty member who recently went to work for the University of Sao Paulo in Brazil, and Leman, onto the project to handle the bioinformatics and statistical aspects of the research, respectively.

First, the scientists needed to map changes in the bacterial pathogen over large spans of time. They compared DNA sequences of bacteria isolated in multiple years, dating back to 1960 and stored since then in international culture collections. Setubal, along with Nalvo Almeida, an associate professor at the Federal University of Mato Grosso do Sul, provided automated genome annotation and helped Vinatzer with identification and analysis of mutations that distinguished the sequenced genomes.

"One of the questions we asked was, did the bacteria isolated in 2000 directly evolve from the bacteria isolated in 1975, or did they evolve independently from an ancestor that lived further back in time, maybe 100 to 200 years ago?" said Vinatzer.

To answer this question, Leman, Vinatzer, and Rongman Cai of Lixian, China, a Ph.D. student in plant pathology, physiology, and weed science at Virginia Tech, used statistical methods to correlate the differences in the DNA sequences between the isolated bacteria with the years in which they were isolated to determine if the bacteria progressively became more different from the first bacteria isolated in 1960.

The research team found that the pathogen likely evolved on a relatively recent time scale and continues to adapt to the tomato by minimizing its recognition by the tomato immune system. This suggests that new pathogen variants with increased virulence are spreading around the globe unobserved, presenting a potential threat to biosecurity. Ultimately, it calls for more precise methods of pathogen identification to replace outdated taxonomic descriptions that were established at a time when it was impossible to classify bacteria precisely because the necessary molecular techniques had not been developed yet.

This particular pathogen is important to study because "it has been used as a model pathogen by many labs around the world and is economically significant because it reduced tomato quality and yield," said Vinatzer. He is extending the research project to investigate where the pathogen originally evolved, how it is spreading around the globe, and what can be done to interfere with its spread, including how the tomato might be engineered to be more resistant to the pathogen.

###

Virginia Tech: http://www.vtnews.vt.edu

Thanks to Virginia Tech for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 42 time(s).

Source: http://www.labspaces.net/114918/Research_team_unravels_tomato_pathogen_s_tricks_of_the_trade

2012 camry endometriosis 9 9 9 plan 9 9 9 plan hell on wheels hell on wheels last house on the left

Valero Energy quadruples 3Q profit (AP)

NEW YORK ? Valero Energy Corp. said Tuesday its profit soared in the third quarter as it cut raw material costs while the price of gasoline and other fuels increased. Valero also boosted production.

America's largest oil refiner reported net income of $1.2 billion, or $2.11 per share, for the three-month period ended Sept. 30. That compares with $292 million, or 51 cents per share, a year earlier.

Revenue increased 60.4 percent to $33.7 billion from $21 billion a year ago.

The results were Valero's best in four years. They also beat Wall Street expectations of $1.80 per share on revenue of $31.4 billion, according to FactSet.

CEO Bill Klesse said this year's rise in oil prices is still "supportive of global demand growth." Western Europe may continue to suffer as it works through a credit crisis, but Klesse said the company sees "continued product demand from international markets."

Yet he warned that its refineries were less profitable in the final three months of the year due to recent price swings for oil and petroleum productions.

Shares fell 69 cents, or 2.8 percent, to $23.91 in premarket trading.

From July to September, the San Antonio company focused on using light-sweet oil varieties that were cheaper than others. One of those varieties was West Texas Intermediate crude, which at times was $20 to $30 per barrel cheaper than Brent crude, the international benchmark oil.

Meanwhile, retail gasoline prices rose 33.1 percent, diesel prices rose 31.8 percent and jet fuel prices rose 46.1 percent.

Valero took advantage of those price increases by cranking up fuel production. Its refineries churned out an average increase of 389,000 barrels per day. The company's production also got a boost in the quarter by the addition of two refineries ? one that was acquired in August, and another that wasn't in operation last year.

The company also reported that its ethanol business more than doubled profits in the quarter and set a company earnings record at $107 million in the quarter. Its retail business, which includes Valero gasoline stations, saw profits drop 8 percent to $97 million.

Source: http://us.rd.yahoo.com/dailynews/rss/energy/*http%3A//news.yahoo.com/s/ap/20111101/ap_on_bi_ge/us_earns_valero_energy

theo epstein darknet james ray act williston nd williston nd mists of pandaria

Wednesday, November 2, 2011

Budget iPad 3 will release gaming potential - In Entertainment

Budget iPad 3 will release gaming potential

The iPad has the tablet crown solid on Apple?s head, but for the device to seriously enter the gaming market in extremely high numbers; it will need to drop the high price tag. The hardware is already there, and graphics in games are amazing, although the device has a price that rivals that of dedicated games consoles.

The real benefits come from the cost of games via cheap apps, and even the costly apps are extremely cheap when compared to those on home systems. Airplay mirroring is pretty cool when paring an Apple TV and iPad, or iPhone/iPod touch, and while the software needs fine tuning to cut out lag at times, we see great potential here.

Apple needs to get the tablet hardware in the hands of gamers who do not have a lot of money, and would not really want to leave their favorite games system, be that an Xbox 360, PS3 or Wii. We believe the right price and package could tempt die-hard gamers to jump to tablet gaming, would you?

What would it take for you to start gaming on an iPad, and what price does the iPad 3 need to be for you to part with the cash?

Source: http://www.inentertainment.co.uk/20111031/budget-ipad-3-will-release-gaming-potential/

jejune who won the glee project who won the glee project full tilt poker full tilt poker shel silverstein dont ask dont tell

Tuesday, November 1, 2011

Bank of America nixes $5 debit card fee

This photo taken Oct. 14, 2011, shows a customer at a Bank of America ATM in Hialeah, Fla. Bank of America Corp. is scrapping its plans to charge a $5 monthly debit card fee. The bank's decision to drop the fee came after a roar of customer outrage in recent weeks over the fee. (AP Photo/Alan Diaz)

This photo taken Oct. 14, 2011, shows a customer at a Bank of America ATM in Hialeah, Fla. Bank of America Corp. is scrapping its plans to charge a $5 monthly debit card fee. The bank's decision to drop the fee came after a roar of customer outrage in recent weeks over the fee. (AP Photo/Alan Diaz)

NEW YORK (AP) ? Bank of America Corp. is scrapping its plan to charge a $5 monthly debit card fee.

The bank's decision to drop the fee came after a roar of customer outrage in recent weeks over the fee. Other major banks, including JPMorgan Chase & Co. and Wells Fargo & Co., already canceled tests of similar debit card fees last week.

SunTrust Banks and Regions Financial Corp. followed suit on Monday.

Anne Pace, a spokeswoman for Bank of America, declined to say whether the company experienced a spike in account closures since announcing the $5 debit card fee in September.

But in a statement Tuesday, Bank of America's co-Chief Operating Officer David Darnell said the decision was based on customer feedback. "Our customers' voices are most important to us. As a result, we are not currently charging the fee and will not be moving forward with any additional plans to do so," he said.

Pace added that a "changing competitive marketplace" also played a role.

The about-face by the banking industry comes amid growing public anger over higher bank fees. A movement to get bank customers switch to credit unions ? started by a Bank of America customer ? had marked this Saturday as "Bank Transfer Day."

A separate online petition asking Bank of America to cancel the $5 fee also had gathered more than 306,000 supporters this week.

"Consumers have the power to make the big banks back down from unfair practices if they raise their voices and vote with their feet and their dollars," Norma Garcia of Consumers Union said in a release Tuesday. In the end, she said Bank of America understood that it risked losing too many customers.

Unlike Chase and Wells Fargo, Bank of America's announcement that it would start charging customers a monthly debit card fee early next year had come without any testing in the marketplace.

Pace said the bank had made the decision based on internal surveys with customers. She declined to detail the nature of those surveys but said that in the past couple of weeks, "customer sentiment changed."

The banking industry's retreat from a debit card fee doesn't mean customers aren't seeing higher fees elsewhere.

This past spring, for example, Bank of America raised the monthly fee on its basic checking account to $12, from $8.95.

The Charlotte, N.C.-based bank is also testing a new menu of checking accounts with monthly fees ranging from $6 to $25 in Arizona, Georgia and Massachusetts. Pace said the pilot program is seeing "good results" and that the bank plans to move ahead with its rollout sometime next year.

Other smaller fees may be nicking away at customer wallets as well. In September, the bank instituted a $5 fee to replace debit cards, with overnight rush delivery costing $20. Both services had previously been free. Bank of America isn't alone either.

Chase this year also doubled the fee on its basic checking account to $12 a month. But the bank says it will end a test in Georgia of a basic checking account that charged a $15 monthly fee.

And like many other banks, Wells Fargo ended its debit rewards program earlier this year.

The wave of fee hikes comes as the industry adjusts to new regulations. A rule that went into effect last month caps the fees banks can collect from merchants whenever customers swipe their debit cards.

Banks in the past year have blamed their fee hikes and pullback on perks on a new federal law championed by Senator Dick Durbin of Illinois. The law, which went into effect last month, caps the amount banks can charge merchants whenever customers swipe their debit cards.

JPMorgan has said it would lose $300 million each quarter as a result of the regulation; Wells Fargo said it would lose $250 million a quarter.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2011-11-01-Debit%20Fees-About-Face/id-6adfa2c1c4f346efa27bd309906c3009

creature us open mens final go daddy tmobile johnny cash serbia spongebob squarepants

NBA: Kris Humphries Robbed for Hundreds of Thousands of Dollars by His Wedding Guest

Kim Kardashian?s husband Kris Humphries claims he was bilked out of hundreds of thousands of dollars by a guy he invited to his wedding ? a guy who?s been arrested for allegedly running a $1.7 million investment scam. ? Read more after the jump.

@Shay_Marie x @gametimegirl

Andrey C. Hicks?was a guest at Kim and?Kris Humphries?televised?wedding bonanza in August ? and sat right behind the happy couple during the?rehearsal dinner.

But TMZ has learned ? after the wedding, Kris learned Andrey was a?target?in a federal investigation in which he?s suspected of raising money for a purported?billion dollar?hedge fund ? that didn?t really exist.

Officials believe Andrey lied to several investors ? including Kris ? telling them, among other things, that he was a Harvard graduate ? when in fact, he was kicked out of the University after 3 semesters for crappy grades. Officials say Andrey only took 1 math class at Harvard ? and got a D-.

Officials claim 27-year-old Hicks stole $1.7 million from various investors ? and sources close to Kris tell us the NBA star accounted for hundreds of thousands of dollars himself.

Hicks was arrested in Canada on Friday and charged with wire fraud. Officials believe he was trying to flee to Switzerland. If convicted, Hicks could face up to 20 years in prison and a $250,000 fine.

TMZ

Source: http://www.inflexwetrust.com/2011/10/29/nba-kris-humphries-robbed-for-hundreds-of-thousands-of-dollars-by-his-wedding-guest/

workaholics new iphone 5 release mary j blige cole hamels cole hamels curtis painter apple news conference